Drug Uses
Endep - popular treatment of depression and insomnia.

How Taken
Endep comes as a tablet to take orally. The general dosage for it is 1–4 times daily. It may be taken with or without a meal. For best effect Endep should be taken regularly for a couple of weeks. Even you feel better do not stop taking Endep without your doctor`s approval. If you have been taking Endep in large doses or for a long time, your doctor will most likely want to gradually lower your dose before you stop taking Endep. Do not take more or less of this drug, than your doctor has prescribed to you.

Missed Dose
If you miss a dose take it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

Storage
Keep the product away heat, moisture and light. The temperature should be between 59–86 °F (15–30 °C). Make sure children cannot reach it.

More Information
You may need a dosage adjustment or special monitoring during treatment, or you may not be able to take this drug at all if you have kidney or liver infection, or if you have gastrointestinal problems. Endep interact with the following products – phenytoin (Dilantin); tamoxifen (Nolvadex); tolbutamide (Orinase); torsemide (Demadex); fluvastatin (Lescol); a blood thinner such as warfarin (Coumadin), heparin, ardeparin (Normiflo), dalteparin (Fragmin), danaparoid (Orgaran), enoxaparin (Lovenox) or tinzaparin (Innohep); (Activase), anistreplase (Eminase), dipyridamole (Persantine), streptokinase (Kabikinase, Streptase), ticlopidine (Ticlid) and urokinase (Abbokinase). Patients taking the above mentioned drugs should consult a doctor concerning the dosage and possibility of Endep usage.

Warnings/Precautions
Endep may cause dizziness or lightheadedness. These effects may worsen if Endep is taken with alcohol or certain medicines. Use Endep Tablets with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to this drug. Do not eat grapefruit or drink grapefruit juice while you take Endep Tablets. Proper dental care is important while you are taking Endep Tablets. Brush and floss your teeth and visit the dentist regularly. If your symptoms do not improve or if they worsen, contact your doctor. Endep should be used only by the patient for whom it has been prescribed. Do not take less or more or take it more often than prescribed by your doctor.

Disclaimer
This is only general information, it does not cover all directions, drug integrations or precautions. You should not rely on it for any purpose, it does not contain any specific instructions for a particular patient. We disclaim all responsibility for the accuracy and reliability of this information. We`re not responsible for any damage.

Possible Side Effects
Among the possible negative side effects are - severe neutropenia (low white blood cells), thrombotic thrombocytopenic purpura (TTP), hemorrhage (gastrointestinal hemorrhage and cerebral hemorrhage), headache, indigestion, flushing. Search medical help if any of these negative side effects do not ease off in several hours. These are not all the side effects of Endep. For more information, ask your doctor or pharmacist.